I think that may be part of the reason why they're introducing different "zones" that you'll basically have to stay within at first in order to avoid being badly outleveled and inferiorly equipped (I.e., a lv. 2 VH vs. a lv. 25 super mutant wouldn't end well for the player...).
Some people might complain about not being able to freely roam the entire map from the start, but I actually think it will be a welcome change.
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