Kang deploys his own evil Avengers in the form of Steve Rogers (Secret Empire variant), Tony Stark, and Natasha Romanov (if she took over Drakov's operation). This idea not only resurrects fan faves, but mixes nicely with One Who Remain's philosophy about how worse things could get with timeliness diverging out of control. Does sound like wishful thinking, but sound attraction for a big finale.
Peter 2 and Peter 3 returns. While Tobey's return is actually substantiated by his interest in returning to the role, Andrew's involvement is whispered to follow an Amazing 3 movie. Of course this is tied up with Sony's silliness but if the latter is true then that makes for weight toward another tidbit - Emma Stone as Gwen variant Spider-Gwen.
There's this messy mixed messages about which Secret Wars will have more influence, but it seems entirely predicated on the OG story giving Peter 1 his black suit. And people really want this to happen and that's kinda skewing the good dirtsheets from wishlists. Given all this multiverse stuff it's very likely the modern Secret Wars with battle world and all that. But yeah, Tom may get his edgy moment.
The multiverse will end with a new One Who Remains (a Kang variant again) and a new Sacred Timeline. And those Mutants? Well the reason, and this is all my speculation, for Kevin waiting so long to pull the trigger is because they are probably going to put the MCU on their back. Like the Avengers who's heroes drove the bulk of MCU's events it'll be the X-Men driving the MCU - with an X-Men film being the big finales of a phase. They pretty much burned thru half a century of 616 canon with the Avengers and the X-Men have another half century more of plots for another decade of MCU.
But who knows.